I recently purchased a Radeon Vega 56 graphics card to go in my PC. I already have a a Quadro M2000, which is good in that it does 10 bit OpenGL (i.e. Photoshop can use it for 10 bit output), but it isn't very good for running modern games. So I purchased the Radeon card for that purpose, and it should also work well for other tasks with its 8GB of HBM2 memory.
Before I purchased the card I spent quite a while researching if the two cards could be used together. There seemed to be various conflicting information. From what I read, it seems that with NVIDIA cards you used to be able to run a Geforce and a Quadro at the same time, but that is no longer possible. It also seems that running a Radeon and Radeon Pro in the same system is not possible. Running a Radeon and a Quadro seemed possible, so long as both are not in use at the same time.
The advice seemed to be to set up dual boot - one OS that has drivers for the Pro card while the non-pro card is disabled. Then another OS for the non-pro card, with the Pro card disabled.
Well, I installed the Radeon in my system, and it seems to work okay without any messing - I can have one monitor in my Quadro, one in the Radeon, and no crashes or anything. The card performance does seem rather limited and I did get crashing when I tried undervolting it. But I suspect this is down to silicon lottery / useless reference cooler rather than any driver clashes.
Something I haven't tried yet is connecting both cards to my main monitor (so I can switch input on the monitor to switch between which card the monitor is running off), but I can't see there being any issues.
Of course, I can't say that all Radeon cards work okay with all Quadros, but at least in my experience it works okay for the two cards I have on my system.
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